LEESGGGLVQPGGSMK acetate is a proteolysis peptide and a component of Infliximab. It is utilized for the quantitative analysis of Infliximab, which is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Anti-TNF antibodies have transformed the therapy of TNF-related diseases including Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and rheumatoid arthritis, by neutralizing TNF activity. These antibodies promote mucosal healing and induce long-term remissions in vivo.
- Proteolysis peptide
- Component of Infliximab
- Used for quantitative analysis of Infliximab
- Chimeric monoclonal IgG1 antibody that specifically binds to TNF-α
- Anti-TNF antibodies block the action of TNF alpha
- Revolutionized therapy for TNF-related diseases
- Neutralizes TNF activity
- Promotes mucosal healing
- Induces long-term remissions in vivo